Coding

Part:BBa_K2365518:Design

Designed by: Liu Zhaoxi   Group: iGEM17_NAU-CHINA   (2017-10-23)


BI-1 coding sequences


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BamHI site found at 493
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

It can be used to protect yeasts. And it can be used to design yeast kill switch in combination with Bax.


Source

The sequences come from NCBI nucleotide database (XM_035490.1).

References

Xu, Q., and J. C. Reed. "Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast." Molecular Cell 1.3(1998):337.

Hückelhoven, R. "BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives. " Apoptosis An International Journal on Programmed Cell Death 9.3(2004):299-307.

Henke, N, et al. "The ancient cell death suppressor BAX inhibitor-1." Cell Calcium 50.3(2011):251-60.